Detection of Cutaneous Blood Flow Changes Associated with Diabetic Microangiopathies in Type 2 Diabetes Patients Using Incoherent Optical Fluctuation Flowmetry

The aim of the present study was to evaluate changes in cutaneous blood flow detected by incoherent optical fluctuation flowmetry (IOFF) diabetic patients with diagnosed microangiopathies. includes 52 type 2 diabetes mellitus (12 males, 40 females, median age 57 (51; 60) years). All were examined using IOFF method functional tests: occlusion test on index finger, local heat dorsum foot, and big toe. divided into groups: 13 both retinopathy nephropathy (Group 2, severe microcirculatory disorders) 39 only 1 microangiopathic complication or without any 1). Local thermal hyperaemia (LTH2_1) higher Group than (p = 0.011). Post-occlusive reactive (PORH_2) 0.009). No When PORH_2 LTH2_1 used combination, area under ROC curve (95% CI) 0.733 (0.62 0.846). Thus, has potential accurately detect abnormalities associated